The NIMA Kinase Is Required To Execute Stage-Specific Mitotic Functions after Initiation of Mitosis
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چکیده
منابع مشابه
Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis*
INCENP, Borealin, Survivin, and Aurora B kinase comprise the chromosomal passenger complex, an essential regulator of mitotic events. INCENP (inner centromere protein) binds and activates Aurora B through a feedback loop involving phosphorylation of a Thr-Ser-Ser (TSS) motif near the INCENP C terminus. Here, we have examined the role of the TSS motif in vertebrate cells using an DT40 INCENP(ON/...
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Intercellular bridges are a conserved feature of multicellular organisms. In multicellular fungi, cells are connected directly via intercellular bridges called septal pores. Using Aspergillus nidulans, we demonstrate for the first time that septal pores are regulated to be opened during interphase but closed during mitosis. Septal pore-associated proteins display dynamic cell cycle-regulated lo...
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ژورنال
عنوان ژورنال: Eukaryotic Cell
سال: 2013
ISSN: 1535-9778,1535-9786
DOI: 10.1128/ec.00231-13